Researcher: Assoc. Prof. Bissera Pilicheva


Department of Pharmaceutical sciences, Medical University of Plovdiv,

E-mail address:


Bissera Pilicheva is an Associate Professor and Head of the Department of Pharmaceutical sciences at MU-Plovdiv. She is a graduated pharmacist, holds a PhD in Pharmaceutical technology and biopharmacy. Specialist in Pharmaceutics and biopharmaceutics and in Clinical pharmacy. She has professional experience as a researcher at University of Tromso, Norway and University of Szeged, Hungary. Team leader and member of numerous national research and educational projects. Leader of the Formulation and drug delivery research group of the Faculty of pharmacy, Medical University of Plovdiv. Her professional expertise is in the field of pharmaceutics and drug delivery including particulate drug delivery systems for alternative routes of administration, targeted drug delivery, personalized medicine.

Selected Publications:

1. Pilicheva B, Boyuklieva R. Can the Nasal Cavity Help Tackle COVID-19? Pharmaceutics, 2021; 13(10), 1612.
2. Katsarov P, Shindova M, Lukova P, Belcheva A, Delattre C, Pilicheva B. Polysaccharide-Based Micro- and Nanosized Drug Delivery Systems for Potential Application in the Pediatric Dentistry. Polymers, 2021, 13, 3342.
3. Pilicheva B, Uzunova Y, Katsarov P. Comparative Study on Microencapsulation of Lavender (Lavandula angustifolia Mill.) and Peppermint (Mentha piperita L.) Essential Oils via Spray-Drying Technique. Molecules, 2021, 26, 7467.
4. Zahariev N, Marudova M, Milenkova S, Uzunova Y, Pilicheva B. Casein Micelles as Nanocarriers for Benzydamine Delivery. Polymers, 2021, 13, 4357.
5. Georgieva Y, Kassarova M, Kokova V, Apostolova E, Pilicheva B. Taste masking of enalapril maleate by microencapsulation in Eudragit EPO® microparticles. Die Pharmazie - An International Journal of Pharmaceutical Sciences, 2020, 75 (2-3), 61-69.
6. Pilicheva B, Uzunova Y, Bodurov I, Viraneva A, Exner G, Sotirov S, Yovcheva T, Marudova M. Layer-by-layer self-assembly films for buccal drug delivery: The effect of polymer cross-linking. Journal of Drug Delivery Science and Technology. 2020, 59.
7. Exner G, Marudova M, Sotirov S, Marinova A, Viraneva A, Pilicheva B, Bodurov I, Vlaeva I, Uzunova Y, Yovcheva T. Multilayered polyelectrolyte structures with potential for intracavity drug delivery systems. Applied Surface Science. 2019, 493, 620-627.
8. Marudova M, Exner G, Pilicheva B, Marinova A, Viraneva A, Bodurov I, Sotirov S, Vlaeva I, Uzunova Y, Yovcheva T. Effect of assembly pH and ionic strength of chitosan/casein multilayers on benzydamine hydrochloride release. International Journal of Polymeric Materials and Polymeric Biomaterials, 2019, 68(1-3).
9. Katsarov P, Pilicheva B, Uzunova Y, Gergov G, Kassarova M. Chemical cross-linking: A feasible approach to prolong doxylamine/pyridoxine release from spray-dried chitosan microspheres. European Journal of Pharmaceutical Sciences, 2018, 123, 387-394.
10. Pilicheva B, Draganova-Filipova M, Zagorchev P, Kassarova M. Investigation of betahistine dihydrochloride biocompatibility and nasal permeability in vitro. Journal of Applied Biomedicine, 2016, 14(4), 299-305. doi: 10.1016/j.jab.2016.06.001